An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function.

Liu L, Westler WM, den Boon JA, Wang X, Diaz A, Steinberg HA, Ahlquist P.

PLoS Pathog. 2009 Mar;5(3):e1000351. Epub 2009 Mar 27. [Link to article]


Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution.
Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB.
Science. 2009 Apr 3;324(5923):55-9. Epub 2009 Feb 12. [Link to article]





Fabrication of Microbial Biofilm Arrays by Geometric Control of Cell Adhesion.
Eun YJ, Weibel DB.
Langmuir. 2009 Feb 12. [Link to article]






The pipeline. Scientific teaching in practice

Miller S, Pfund C, Pribbenow CM, Handelsman J.

Science. 2008 Nov 28;322(5906):1329-30 [Link to article]



Adipocyte metabolism and obesity.

Attie AD, Scherer PE.

J Lipid Res. 2008 Nov 17. [Link to article]






The interaction between an acidic transcriptional activator and its inhibitor. The molecular basis of Gal4p recognition by Gal80p.

Thoden JB, Ryan LA, Reece RJ, Holden HM.

J Biol Chem. 2008 Oct 31;283(44):30266-72. Epub 2008 Aug 13 [Link to article]



Evolution of our understanding of vitamin D

DeLuca HF.

Nutr Rev. 2008 Oct;66(10 Suppl 2):S73-87. [Link to article]




How to get a cow pregnant

Grow  Magazine, Fall 2008, Wisconsin's Magazine for the Life Sciences






In Planta Analysis of the Cell Cycle-Dependent Localization of AtCDC48A and Its Critical Roles in Cell Division, Expansion, and Differentiation

Sookhee Park, David Michael Rancour, and Sebastian York Bednarek

Plant Physiology, Sep 2008; 148: 246 - 258. [Link to article]








A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity

Craig R. Stumpf, Judith Kimble, and Marvin Wickens

RNA, Aug 2008; 14: 1550 - 1557. [Link to article]









Structure, mechanism and regulation of pyruvate carboxylase.

Jitrapakdee S, St Maurice M, Rayment I, Cleland WW, Wallace JC, Attwood PV.

Biochem J. 2008 Aug 1;413(3):369-87 [Link to article]





How to make DNA

Grow  Summer 2008, Wisconsin's Magazine for the Life Sciences




A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
Keller MP, Choi Y, Wang P, Belt Davis D, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD
Genome Res. 2008 May;18(5):706-16. [Link to article]


Direct NMR Detection of the Binding of Functional Ligands to the Human Sweet Receptor, a Heterodimeric Family 3 GPCR
Fariba M. Assadi-Porter, Marco Tonelli, Emeline Maillet, Klaas Hallenga, Outhiriaradjou Benard, Marianna Max,‡ and John L. Markley
J. Am. Chem. Soc., 130 (23), 7212–7213, 2008.



The C. elegans SYS-1 protein is a bona fide beta-catenin.

Liu J, Phillips BT, Amaya MF, Kimble J, Xu W.

Dev Cell. 2008 May;14(5):751-61. [Link to article]




Isotope-coded affinity tags with tunable reactivities for protein footprinting.

Underbakke ES, Zhu Y, Kiessling LL.

Angew Chem Int Ed Engl. 2008;47(50):9677-80. [Link to article]




Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly.

Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ.

ACS Chem Biol. 2008 Apr 18;3(4):220-9. [Link to article]




Structural dependencies of protein backbone 2JNC couplings

Nenad Jurani, J.J. Dannenberg, Gabriel Cornilescu, Pedro Salvador, Elena Atanasova, Hee-Chul Ahn, Slobodan Macura, John L. Markley, Franklyn G. Prendergast.

Protein Sci. 2008 Apr;17(4):768-76. Epub 2008 Feb 27.[Link to article]




Bright ideas for chemical biology.

Lavis LD, Raines RT.

ACS Chem Biol. 2008 Mar 20;3(3):142-55. Review. [Link to article]





A rapid, microplate SNP genotype assay for the leptinob allele.
Oler AT, Attie AD.J
Lipid Res. 2008 May;49(5):1126-9. Epub 2008 Feb 13.





How to study the smell of cheese

Grow    Winter 2008, Wisconsin's Magazine for the Life Sciences





Synaptotagmin C2A Loop 2 Mediates Ca2+-dependent SNARE Interactions Essential for Ca2+-triggered Vesicle Exocytosis

K. L. Lynch, R.R.L. Gerona, E. C. Larsen, R. F. Marcia, J. C. Mitchell, and T.F.J. Martin

Mol Biol Cell. 2007 Dec;18(12):4957-68. [Link to article]








How to see a protein

Grow    Fall 2007, Wisconsin's Magazine for the Life Sciences




Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers.

Derda R, Wherritt DJ, Kiessling LL.

Langmuir. 2007 Oct 23;23(22):11164-7. Epub 2007 Sep 20.[Link to article]





Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme

St Maurice M, Reinhardt L, Surinya KH, Attwood PV, Wallace JC, Cleland WW, Rayment I.

Science. 2007 Aug 24;317(5841):1076-9 [Link to article]




Defined substrates for human embryonic stem cell growth identified from surface arrays.

Derda R, Li L, Orner BP, Lewis RL, Thomson JA, Kiessling LL.

ACS Chem Biol. 2007 May 22;2(5):347-55. [Link to article]





Activating B cell signaling with defined multivalent ligands.

Puffer EB, Pontrello JK, Hollenbeck JJ, Kink JA, Kiessling LL.

ACS Chem Biol. 2007 Apr 24;2(4):252-62. [Link to article]




1,25-Dihydroxyvitamin D3 induces expression of the Wnt signaling co-regulator LRP5 via regulatory elements located significantly downstream of the gene's transcriptional start site.

Fretz JA, Zella LA, Kim S, Shevde NK, Pike JW.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):440-5. [Link to article]




ABCA1: at the nexus of cholesterol, HDL and atherosclerosis.

Attie AD.

Trends Biochem Sci. 2007 Apr;32(4):172-9. Epub 2007 Feb 26. Review. [Link to article]




Selective tumor cell targeting using low-affinity, multivalent interactions.

Carlson CB, Mowery P, Owen RM, Dykhuizen EC, Kiessling LL.

ACS Chem Biol. 2007 Feb 20;2(2):119-27. [Link to article]






Regulation of bacterial RecA protein function.

Cox MM.

Crit Rev Biochem Mol Biol. 2007 Jan-Feb;42(1):41-63. Review. [Link to article]




Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.

Thoden JB, Sellick CA, Reece RJ, Holden HM.

J Biol Chem. 2007 Jan 19;282(3):1534-8. Epub 2006 Nov 22 [Link to article]


Enhancers located in the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.

Zella LA, Kim S, Shevde NK, Pike JW.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):435-9. Epub 2007 Jan 10. [Link to article]


Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3.

Kim S, Yamazaki M, Zella LA, Meyer MB, Fretz JA, Shevde NK, Pike JW.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):430-4. Epub 2007 Jan 2. [Link to article]




Positional cloning of a type 2 diabetes quanitative trait locus.

Clee, S.M., Yandell, B.S., Schueler, K.M., Rabaglia, M.E., Richards, O.C., Raines, S.M., Kabara, E.A., Klass, D.M., Stapleton, D.S., Gray-Keller, M.P., Boronenkov, I., Raess, P.W., Flowers, M.T., and Attie, A.D.

Nature Genetics 38,688-693 2006[Link to article]





Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.

Zella LA, Kim S, Shevde NK, Pike JW

Mol Endocrinol. 2006 Jun; 20(6):1231-47 [Link to article]






Membrane Association, Mechanism of Action, and Structure of Arabidopsis Embryonic Factor 1 (FAC1)

Byung Woo Han, Craig A. Bingman, Donna K. Mahnke, Ryan M. Bannen, Sebastian Y. Bednarek, Richard L. Sabina, and George N. Phillips, Jr.

J. Biol. Chem., May 2006; 281: 14939 - 14947. [Link to article]